Primary pulmonary NK/T cell lymphoma: report of a rare entity and review of literature
نویسندگان
چکیده
Primary pulmonary NK/T cell lymphoma is extremely rare. The authors reported a case of primary pulmonary NK/T cell lymphoma in a 47-year-old man presented with fever, cough, and chest pain. Morphologically, an angiocentric/angiodestructive growth pattern with coagulative necrosis was observed. On immunohistochemical staining, the atypical lymphocytes showed TIA-1+, CD56+, Ki-67 40%+, Cytokeratin-, CD30-, ALKand CD20-. In Situ hybridization, most atypical lymphocytes had positive staining for Epstein-Barr virus encoded RNA. All of above findings were consistent with NK/T cell lymphoma. The patient’s general status was improved after chemotherapy of VIPD. We also reviewed the clinical and pathological characteristics of primary pulmonary NK/T cell lymphoma which have been published in the literature.
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